[Download] "Trials and Tribulations." by The Hastings Center Report # Book PDF Kindle ePub Free
eBook details
- Title: Trials and Tribulations.
- Author : The Hastings Center Report
- Release Date : January 01, 2008
- Genre: Life Sciences,Books,Science & Nature,
- Pages : * pages
- Size : 150 KB
Description
By all accounts, Jolee Mohr was an active woman in relatively good health. Though she had rheumatoid arthritis, it did not keep her from holding down an office job and spending her leisure time boating with her husband and their young daughter. But the thirty-six-year-old Illinois woman's life came to an unexpected end last July, three weeks after an experimental gene therapy was injected into her right knee during a phase I/II clinical trial aimed only at assessing the agent's toxicity. Mohr's rheumatologist had recruited her for the study and had given her the injection in his office. Her death was caused by organ failure from histoplasmosis, a common fungal infection that normally produces only mild illness. The tragedy immediately sparked comparisons with the story of Jesse Gelsinger, a vital eighteen-year-old who died in 1999 during a gene therapy trial at the University of Pennsylvania. Gelsinger's death was the first to be definitively linked to a gene therapy trial. Would Mohr's be another? The trial was halted pending an investigation by the National Institutes of Health's Recombinant Advisory Committee.